Publikationen
Übersicht
Originalarbeiten
2022
- Kammerl I, Hardy S, Flexeder C, Urmann A, Peierl J, Wang Y, Vosyka O, Frankenberger M, Milger K, Behr J., Koch A, Merl-Pham J, Hauck SM, Pilette C, Schulz H, Meiners S.
Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy.
Eur Resp J 2022;59:2101798 [IF 16,7]
- Franziska C. Trudzinski, Rudolf A. Jörres, Peter Alter, Julia Walter, Henrik Watz, Andrea Koch, Matthias John, Marek Lommatzsch, Claus F. Vogelmeier.
Sex-specific associations of comorbidome and pulmorbidome with mortality in chronic obstructive pulmonary disease: results from COSYCONET
Sci Rep 2022;12(1):8790 [IF 4,4]
2021
- Carlo Mümmler, Kristin Dünzelmann, Nikolaus Kneidinger, Michaela Barnikel, Dieter Munker, Moritz Gröger, Martin Canis, Jürgen Behr, Andrea Koch, Frank Haubner, Katrin Milger
Real-life effectiveness of biological therapies on symptoms in severe asthma with comorbid CRSwNP.
Clin Transl Allery 2021;11(5):e12049.doi:10.1002 [IF 3,6]
- Jürgen Behr, Antje Prasse Michael Kreuter, Johannes Johow, Klaus Rabe,…. Andreas Günther & Relief Investigators (Andrea Koch….)
Pirfenidone in patients with progressive fibrotic interstitial lung diseases othr than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebocontrolled, phase 2b tail.
Lancet Respir Med 2021;9(5):476 [IF 30,7]
- Kaschin JJ, Gallert WJ, Yanik SD, Panek S, Kronsbein J, Jungck D, Koch A, Knobloch J
Biomarkers for comorbidities modulate the activtiy of T-cells in COPD
Int J Mol Sci 2021;22(13):7187 [IF 5.9]
2018 - 2020
- Jürgen Knobloch, Swaantje Casjens, Martin Lehnert, Sarah D Yanik, Sandra Körber, Anne Lotz, Jan Rupp, Monika Raulf, Wolfgang Zschiesche, Tobias Weiss, Juliane Kronsbein, Andrea Koch, Thomas Brüning, Beate Pesch
Exposure to welding fumes suppresses the activity of T-helper cells
Environ Res 2020;189:109913:doi:10.1016/j.envres.2020.109913. Epub 2020 Jul 12 [IF 5.0]
- Knobloch J, Jungck D, Kronsbein J, Stoelben E, Ito K, Koch A.
LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD.
J Clin Med. 2019 Nov 22;8(12). pii: E2058. doi: 10.3390/jcm8122058 [IF 5.7]
- Jürgen Knobloch, Susanne Panek, Sarah Yanik, Kaschin Jamal Jameel, Zeynep Bendella, David Jungck, Paul Bürger, Eike Bülthoff, Birte Struck, Nikolaos Giannakis, Jan Rupp, Juliane Kronsbein, Marcus Peters, Andrea Koch
The monocyte-dependent immune response to bacteria is suppressed in smokinginduced COPD
J Mol Med 2019;97(6):817-28 [IF 4.8]
- Koch A, Behr J.
Cough and its differential diagnosis.
Dtsch Med Wochenschr 2018;143:1258-1271 [IF 0.52]
- Matthes S, Stadler J, Barton J, Leuschner G, Munker D, Arnold P, Villena-Hermoza H, Frankenberger M, Probst P, Koch A, Kneidinger N, Milger K, Behr J, Neurohr C
Asthma features in severe COPD: Identifying treatable traits.
Respir Med 2018;145:89-94 [IF 3.7]
- Maltais F, Buhl R, Koch A, Amatto VC, Reid J, Grönke L, Bothner U, Voß F, McGarvey L, Ferguson GT.
ß-blockers in Chronic Obstructive Pulmonary Disease: a Cohort Study from the TONADO Research Programme.
Chest 2018;153(6):1315-25 [IF 6.15]
- Knobloch J, Jungck D, Charron C, Stoelben E, Ito K, Koch A.
Superior anti-inflammatory effects of narrow-spectrum kinase inhibitors in airway smooth muscle cells from subjects with chronic obstructive pulmonary disease.
J Allergy Clin Immunol 2018,141:1122-1124] [IF: 13.1]
1992 - 2017
- Koch A, Watz H, M,Maleki-Yazdi R, Bothner U, Tetzlaff K, Voß F and McGarvey L.
Comprehensive assessment of the safety of olodaterol 5 μg in the Respimat® device for maintenance treatment of COPD: comparison with the long-acting β2-agonist formoterol
Primary Care Resp Med 2017;27(1):60] [IF 1.9]
- Knobloch J, Jungck D, Koch A.
The molecular mechanisms of thalidomide teratogenicity and implications for modern medicine.
Curr Mol Med 2017;17(2):108 [IF: 2.35]
- Witzke KE, Rosowski K, Müller C, Ahrens M, Eisenacher M, Megger DA Knobloch J, Koch A, Bracht T, Sitek B
Quantitative secretome analysis of activated jurkat cells using click chemistry-based enrichment of secreted glycoproteins.
J Proteome Res 2017;16(1):137-146 [IF:4.27]
- Kalbe B, Knobloch J, Schulz VM, Wecker C, Schlimm M, Scholz P, Jansen F, Stoelben E, Philippou S, Hecker E, Lübbert H, Koch A, Hatt H, Ostreloh S.
Olfactory receptores modulate physiological processes in human airway smooth muscle cells.
Front Physiol 2016;7:339 [IF:3.92]
- KnoblochJ, Yanik SD, Körber S, Stoelben E, Jungck D, Koch A.
TNFα-induced airway smooth muscle cell proliferation depends on endothelin receptor signaling, GM-CSF and IL-6.
Biochem Pharmacol 2016;116:188-99 [IF: 5.1]
- Knobloch J, Chikosi SJ, Yanik S, Rupp J, Jungck D, Koch A
A systemic defect in Toll-like receptor 4 signaling increases lipopolysaccharideinduced suppression of IL-2-dependent T-cell proliferation in COPD.
Am J Physiol Lung Cell Mol Physiol 2016;310(1):L24-39 [IF:4.1]
- Knobloch J, Yakin Y, Körber S, Grensemann B, Mt Z, Boyaci N, Gallert WJ, Yanik S, Jungck D, Koch A.
Simvastatin requires activation in accessory cells to modulate T-cell responses in Asthma and COPD.
Eur J Pharmacol 2016;788:294-305 [IF: 2.7]
- Gerlach K, Köhler-Bachmann S, Jungck D, Körber S, Yanik S, Knoop H, Wehde D, Rheinländer S, Walther JW, Kronsbein J, Knobloch J, Koch A
Endothelin receptor-antagonists suppress lipopolysaccharide-induced cytokine release from alveolar macrophages of non-smokers, smokers and COPD subjects.
Eur J Pharmacol 2015;768:123-30 [IF: 2.7]
- Behr J, Kreuter M, Hoeper MM, Wirtz H, Klotsche J, Koschel D, Andreas S, Claussen M, Grohe C, Wilkens H, Randerath W, Skowasch D, Meyer FJ, Kirschner J, Gläser S, Herth FJ, Welte T, Huber RM, Neurohr C, Schwaiblmair M, Kohlhäufl M, Höffken G, Held M, Koch A, Bahmer T, Pittrow D.
Management of patients with idiopathic pulmonary fibrosis in clinical practice: the INSIGHTS-IPF registry.
Eur Respir J 2015;46(1):186-96 [IF: 7.1]
- Jungck D, Knobloch J, Koerber S, Lin Y, Konradi J, Yanik S, Stoelben E, Koch A
Endothelin Receptor B Protects Granulocyte Macrophage Colony Stimulating Factor mRNA from Degradation.
J Pharmacol Exp Ther 2015;353(3):564-72 [IF: 3.8]
- McGarvey L, Niewoehner D, Magder S, Sachs P, Tetzlaff K, Hamilton A, Korducki L, Bothner U, Vogelmeier C, Koch A, Ferguson GT.
One-Year Safety of Olodaterol Once Daily via Respimat® in Patients with GOLD 2-4 Chronic Obstructive Pulmonary Disease: Results of a Pre-Specified Pooled Analysis.
COPD 2015;12(5):484-493 [IF 2,6]
- Koch A, Pizzichini E, Hamilton A, Hart L, Korducki L, De Salvo MC, Paggiaro P.
Lung function efficacy and symptomatic benefit of olodaterol once daily delivered via Respimat versus placebo and formoterol twice daily in patients with GOLD 2-4 COPD: results from two replicate 48-week studies.
Int J Chron Obstruct Pulmon Dis 2014;9:697-714 [IF: 2.7]
- Knobloch J, Wahl C, Feldmann M, Jungck D, Strauch J, Stoelben E, Koch A.
Resveratrol attenuates the release of inflammatory cytokines from human bronchial smooth muscle cells exposed to lipoteichoic acid in chronic obstructive pulmonary disease.
Basic Clin Pharmacol Toxicol 2014;114(2):202-9 [IF: 3.8]
- Magnussen H et al. WISDOM Investigators: Koch A. and others
Withdrawal of inhaled glucocorticoids and exacerbations of COPD
N Engl J Med 2014;371(14):1285-94 [IF: 53.3]
- Knobloch J, Feldmann M, Wahl C, Jungck D, Behr J, Stoelben E, Koch A.
Endothelin receptor antagonists attenuate the inflammatory response of human pulmonary vascular smooth muscle cells to bacterial endotoxin.
J Pharmacol Exp Ther 2013; 346(2):290-9 [IF: 3.8]
- Knobloch J, Lin Y, Konradi J, Jungck D, Behr J, Strauch J, Stoelben E, Koch A.
Inflammatory responses of airway smooth muscle cells and effect of endothelin receptor antagonism.
Am J Respir Cell Mol Biol 2013; 49(1):114-27 [IF: 5.1]
- Mat Z, Grensemann B, Yakin Y, Knobloch J, Koch A.
Effect of Lipoteichoic Acid On IL-2 and IL-5 Release from T lymphocytes in Asthma and COPD.
Int Immunopharmacol 2012; 13: 184-191 [IF: 2.4]
- Vogelmeier C, Hederer B, Glaab T, Schmidt H, Rutten-van Mölken MP, Beeh KM, Rabe KF, Fabbri LM and POET-COPD Investigators: Koch A and others.
Tiotropium versus salmeterol for the prevention of exacerbations of COPD
N Engl J Med 2011; 24;364(12):1093-1103. [IF: 53.3]
- Knobloch J, Schild K, Jungck D, Urban K, Müller K, Schweda EK, Rupp J, Koch A.
The T-Helper Cell Type 1-Immune Response to Gram-Negative Bacterial Infections is Impaired in COPD.
Am J Respir Crit Care Med 2011; 183: 204-214. [IF: 11.9]
- Knobloch J, Hag H, Jungck D, Urban K, Koch A.
Resveratrol Impairs the Release of Steroid-resistant Cytokines from Bacterial Endotoxin-Exposed Alveolar Macrophages in COPD.
Basic Clin Pharmacol Toxicol 2011; 109: 138-143. [IF: 2.2]
- Schild K, Knobloch J, Yakin Y, Jungck D, Urban K, Müller K, Koch A.
IL-5 Release of CD4+ Non-Effector Lymphocytes is Increased in COPD - Modulating Effects of Moxifloxacin and Dexamethasone.
Int Immunopharmacol 2011; 11: 444-448. [IF: 2.4]
- Knobloch J, Sibbing B, Jungck D, Lin Y, Urban K, Stoelben E, Strauch J, Koch A.
Resveratrol impairs the release of steroid-resistant inflammatory cytokines from human airway smooth muscle cells in COPD.
J Pharmacol Exp Ther 2010; 335: 788-798. [IF: 3.8]
- Knobloch J, Peters H, Jungck D, Müller K, Strauch J, Koch A.
TNFalpha-induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism.
Thorax 2009; 64: 1044-1052. [IF: 8,5]
- Koch A, Knobloch J, Dammhayn C, Raidl M, Ruppert A, Hag H, Rottlaender D, Müller K, Erdmann E.
Effect of bacterial endotoxin LPS on expression of INF-gamma and IL-5 in Tlymphocytes from asthmatics.
Clin Immunol 2007; 125: 194-204. [IF: 4.0]
- Raidl M, Sibbing B, Strauch J, Müller K, Nemat A, Schneider PM, Erdmann E, Koch A.
Impaired TNF-induced VEGF expression in human airway smooth muscle cells from smokers with COPD – role of MAPkinases and histone acetylation – effect of dexamethasone.
Cell Biochem Biophys 2007; 49(2):98-110 [IF: 3.7]
- Koch A, Raidl M, Lux M, Müller K, Büning H, Humme S, Erdmann E.
IL-12-induced T-bet expression and IFN-γ release in lymphocytes from asthmatics – role of MAPkinases ERK-1/-2, p38MAPK and effect of dexamethasone.
Respir Med 2007; 101:1321-1330 [IF: 2.5]
- Koch A, Gaczkowski M, Sturton G, Staib P, Schinköthe T, Klein E, Rubbert A, Bacon K, Waßermann K, Erdmann E.
Modifications of surface antigens in blood CD8+-T-lymphocytes in COPD – effect of smoking.
Eur Respir J 2007;29:42-50 [IF: 7,1]
- Koch A, Giembycz M, Stirling RG, Lim S, Adcock I, Waßermann K, Erdmann E, Chung KF.
Effect of smoking on MAPkinase-induced modulation of IL-8 in human alveolar macrophages.
Eur Respir J 2004;23:805-812. [IF: 7,1]
- Koch A, Giembycz M, Ito K, Lim S, Jazrawi E, Barnes PJ, Adcock I, Erdmann E, Chung KF.
Mitogen-activated protein kinase modulation of nuclear factor-кB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.
Am J Respir Cell Mol Biol 2004 (30):242-349. [IF: 5.1]
- Koch A, Nasuhara Y, Barnes PJ, Lindsay MA, Giembycz MA.
Extracellular signal-regulated kinase 1 / 2 control Ca2+-independent force development in histamine-stimulated tracheal smooth muscle.
Br J Pharmacol 2000;131:981-989. [IF: 4.4]
- Waßermann K, Koch A, Warschkow A, Mathen F, Muller-Ehmsen J, Eckel HE.
Measuring in situ central airway resistance in patients with laryngotracheal stenosis.
Laryngoscope 1999;109 (9):1516-20. [IF: 2.0]
- Waßermann K, Koch A, Muller-Ehmsen J, Reuter M, Michel O, Eckel HE.
Clinical and laboratory evaluation of a new thin-walled self-expanding tracheobronchial silicone stent: progress and pitfalls.
J Thorac Cardiovasc Surg 1997;114(4):527-34. [IF: 3.4]
- Rosenkranz S, Waßermann K, Seelig R, Klein R, Koch A, Beuckelmann DJ, Erdmann E.
Value of polymerase chain reaction (PCR) in diagnosis of tuberculosis and mycobacterium infections caused by ubiquitous mycobacteria.
Pneumologie 1997;51(2):78-86.
- Schwinger RHG, Müller-Ehmsen J, Frank K, Koch A, Erdmann E.
Enhanced sensitivity of the failing human myocardium to cardiac glycosides and Na(+)-channel activatiors.
Am Heart J 1996;131(5):988-993. [IF: 4.7]
- Schwinger RHG, Böhm M, Koch A, Schmidt U, Morano I, Eissener HJ, Überfuhr P, Reichart B, Erdmann E.
The failing human heart is unable to use the Frank Starling`s mechanism.
Circ Res 1994;74:959-969. [IF: 9.5]
- Schwinger RHG, Böhm M, Koch A, Morano I, Rüegg JC, Erdmann E.
Inotropic effect of the cardioprotective agent 2,3 Butanedione Monoxime in nonfailing and failing myocardium.
J Pharmacol Exp Ther 1994; 269:778-786. [IF: 3.8]
- Morano I, Hädicke K, Grom S, Koch A, Schwinger RHG, Böhm M, Bartel S, Erdmann E, Krause EG.
Titin, myosin light chains and C-protein in the developing and failing human heart.
J Mol Cell Cardiol 1994; 26: 361-368. [IF: 5.2]
- Schwinger RHG, Böhm M, Koch A, Uhlmann R, Überfuhr P, Kreuzer E, Reichart B, Erdmann E.
Force-frequency-relation in human atrial and ventricular myocardium.
Mol Cell Biochem 1993;119:73-78. [IF: 2.1]
- Schwinger RHG, Böhm M, Uhlmann R, La Rosee K, Koch A, Erdmann E.
Increase of the extracellular magnesium concentration reduces cardiac glycoside toxicity in the human myocardium.
J Pharmacol Exp Ther 1992;263:1352-1359. [IF: 3.8]
- Schwinger RHG, Böhm M, Koch A, Erdmann E.
Force-frequency-relation in human heart failure.
Circulation (letter) 1992;86:2017-2018. [IF: 14.7]
Übersichtsartikel, Reviews
- Koch A, Behr J
Husten Differentialdiagnosen
Dtsch med Wochenschr 2018 143(17):1258-1271
- Koch, A.
Positive Wirkung inhalativer Kortikoide bei Asthma mit < 2 Symptomtagen.
Positive effects of inhaled corticosteroids for asthma with < 2 symptom days.
Pneumologe 2017;14,244-245
- Koch A.
Topic: Asthmatherapie mit Biologica – Stand der Entwicklung.
Pädiatr Allergologie 2013;4:16-21; Review
- Knobloch J, Jungck D, Koch A.
Apoptosis Induction by Thalidomide: critical for Limb Teratogenicity but Therapeutic Potential in Idiopathic Pulmonary Fibrosis?
Curr Mol Pharmacol 2011; 4: 26-61; Review
- ten Freyhaus H, Bäumer AT, Koch A, Rosenkranz S.
Aktuelle Diagnostik und Therapie der pulmonalen Hypertonie.
Atemw.-Lungenkrkh., 2005; 31(3):124-136; Review
- Rosenkranz S, Koch A, Waßermann K.
Off-label = off-legal = illegal ?
Pneumologie 2005;59 (1):9-11, Review
- Koch A.
Neue Aspekte in der Pathophysiologie der chronisch obstruktiven Lungenerkrankung (COPD) im Vergleich zum Asthma bronchiale.
Atemw.-Lungenkrkh 2002;28:585-586; Review
Buchartikel
- Andrea Koch.
Antineoplastische und immunmodulierende Pharmaka – Tyrosinkinase-Inhibitoren und Folsäure-Analoga
aus: Klaus Fricke: NEUE ARZNEIMITTEL, Wissenschaftliche Verlagsgesellschaft mbH
Stuttgart, 2009, Band 18:331-351
- Andrea Koch.
Anticholinergika;
aus: Winfried Randerath: BRONCHIALTHERAPEUTIKA, Medizinischpharmakologisches Kompendium, Wissenschaftliche Verlagsgesellschaft mbH
Stuttgart; 2007, Band 17:236 – 253.
- Andrea Koch.
Mittel bei obstruktiven Atemwegserkrankungen „Tiotropiumbromid“;
aus: Klaus Fricke: NEUE ARZNEIMITTEL, Wissenschaftliche Verlagsgesellschaft mbH
Stuttgart; 2005, Band 15: 685 – 695.29.